[ THE JOURNAL ]

Notes from the clinic.

Field reports from our physicians, deep-dives on biomarkers, and clinical perspective on what longevity medicine actually looks like in practice. Written by the team that builds your programs.

Four Fitness Numbers That Predict Healthspan Better Than Your Scale
FEATURED TRAINING & PHYSICAL PERFORMANCE OCT 8, 2026

Four Fitness Numbers That Predict Healthspan Better Than Your Scale

Grip strength, getting up off the floor, balance and VO2 max predict healthspan better than body weight. What each measures and why all can be trained.

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Tired All the Time? Your Thyroid Deserves More Than One Number
FATIGUE & ENERGY

Tired All the Time? Your Thyroid Deserves More Than One Number

TSH is a good screening test, not the whole story. What free T4 and thyroid antibodies add, the biotin trap, and what else causes constant fatigue.

Estradiol in Men: The Marker That Shapes How TRT Is Managed
HORMONES FOR MEN

Estradiol in Men: The Marker That Shapes How TRT Is Managed

Men need estradiol for bone, libido and mood. How it rises on TRT, why routine aromatase inhibitors aren't recommended, and how it's best managed.

Testosterone by Age: Why Total T Only Tells Half the Story
TESTOSTERONE

Testosterone by Age: Why Total T Only Tells Half the Story

European labs report testosterone in nmol/L, US charts in ng/dL. Why total T alone misleads, and how SHBG, free T and test timing change the picture.

Testosterone in Women: What the Evidence Actually Supports
HORMONES FOR WOMEN

Testosterone in Women: What the Evidence Actually Supports

Women produce testosterone too. Where the evidence for testosterone therapy in women is strong, where it's thin, and how it's prescribed in Europe.

Perimenopause and Blood Tests: When They Help and When They Don’t
MENOPAUSE

Perimenopause and Blood Tests: When They Help and When They Don’t

Hormones swing week to week in perimenopause, so a single test often looks normal. When blood tests help, when they don't, and what to ask instead.

Lp(a): The Heart Risk You Inherit and Only Need to Test Once
BLOOD TESTING & BIOMARKERS

Lp(a): The Heart Risk You Inherit and Only Need to Test Once

Lp(a) is a genetic heart-risk marker that diet barely moves. Why one test is usually enough, and what a high result changes.

Your Cholesterol Is “Fine.” Your ApoB Might Disagree.
LONGEVITY & HEALTHSPAN

Your Cholesterol Is “Fine.” Your ApoB Might Disagree.

LDL cholesterol counts cholesterol. ApoB counts the particles that cause plaque. When the two disagree, and why ApoB sharpens heart-risk assessment.

Training Hard? Your Blood Results Might Be Misleading You
TRAINING & PHYSICAL PERFORMANCE

Training Hard? Your Blood Results Might Be Misleading You

Hard training changes creatinine, liver enzymes and CK. How exercise skews bloodwork, and which markers matter most for people who train.

What Actually Goes Into a Biological Age Score
LONGEVITY & HEALTHSPAN

What Actually Goes Into a Biological Age Score

Epigenetic clocks, blood-based models and more: what biological age scores measure, what a good one can tell you, and what it can't.